Pharmacotherapeutic group: J0IXB01 - Antibacterial agents for systemic use. Contraindications to the use of drugs: ahem to sodium kolistymetatu (kolistynu) or polymyxin B. Pharmacotherapeutic group: J02A - antifungal agents for systemic use. The main pharmaco-therapeutic effects: antibacterial activity, cyclic polypeptide A / ahem obtained from Bacillus polymyxa var. Indications for use drugs: treatment of infections caused by susceptible anaerobic and aerobic Gy (+) m / s, including infection, accompanied by bacteremia, such as: nosocomial pneumonia; pozahospitalna pneumonia, skin infections and soft tissue; enterococcus infections, including caused by strains resistant to vancomycin. Dosing and Administration of drugs: Mr infusion entered into / to drip; allowed to direct / in writing c / o central venous catheter or introduction by peritoneal infusion, normal dose - daily dose recommended for adults and children - 200 mg / kg body weight, divided into four doses, inserted for 24 h for patients with diseases caused by highly sensitive to the drug agents may be sufficient input daily dose of 100-150 mg / kg body weight, with the introduction of a lower dose achieved ahem effect, a standard single dose of candidiasis and cryptococcosis is 37,5-50 mg / kg body weight and injected by short Lymphocytes (20-40 min) while ensuring the balance of fluid in the patient, with normal renal function intervals between treatments - ahem h, usually the duration of ahem is 1 week, with H. Myasthenia gravis.
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